Martin-Luther-Universität Halle-Wittenberg

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Publications of the last 7 years

Publications

Sichhart, Yvonne; Draeger, Birgit (2012) Immunolocalisation of spermidine synthase in Solanum tuberosum. Phytochemistry, in press

Aehle, Elke; Mueller, Ulrike; Eklund, Patrik C.; Willfoer, Stefan M.; Sippl, Wolfgang; Draeger, Birgit (2011)  Lignans as food constituents with estrogen and antiestrogen activity. Phytochemistry 72 (18), 2396-2405

Nadja Grobe, Marc Lamshöft, Robert G. Orth, Birgit Dräger, Toni M.  Kutchan, Meinhart H. Zenk, Michael Spiteller (2010) Urinary excretion of  morphine and biosynthetic precursors in mice.  Proceedings of the National Academy of Sciences U.S.A. 107, 8147-8152.

Kommera, Harish; Kaluđerović, Goran N.; Kalbitz, Jutta; Dräger,  Birgit; Paschke, Reinhard (2010)  Small structural changes of  pentacyclic lupane type triterpenoid derivatives lead to significant  differences in their anticancer properties. European Journal of Medicinal Chemistry, 45, 3346-3353.

Kommera, Harish; Kaluđerović, Goran N.; Dittrich, Sebastian;  Kalbitz, Jutta; Dräger, Birgit; Mueller, Thomas; Paschke, Reinhard  (2010) Carbamate derivatives of betulinic acid and betulin with  selective cytotoxic activity. Bioorganic & Medicinal Chemistry Letters 20, 3409-3412.

Biastoff, Stefan; Reinhardt, Nicole; Reva, Veaceslav; Brandt, Wolfgang; Dräger, Birgit (2009) Evolution of putrescine N-methyltransferase from spermidine synthase demanded alterations in substrate binding. FEBS Lett. 583, 3367 - 3374.

Biastoff, Stefan; Brandt, Wolfgang; Dräger, Birgit (2009) Putrescine N-methyltransferase - the start for alkaloids. Phytochemistry 70, 1708-18

Mielke, M.C.; Melzer, E.; Serfling, A.; Ahmetovic, U.; Horbach, R.;  Reimann, S.; Wohlrab, J.; Dräger, B.; Deising, H. B. (2008) The  molecular basis of adaptation to fungicides in plant pathogenic  Colletotrichum species. In: Modern Fungicides and Antifungal Compounds, Editors H.-W. Dehne et al.

Müller, Ulrike; Mrestani, Yaya; Neubert, Reinhard; Dräger, Birgit  (2008) Chiral separation of the plant lignan matairesinol by capillary  electrophoresis. Electrophoresis 29, 3582 - 2587

Horn, Gert; Kupfer, Astrid; Kalbitz, Jutta; Gerdelbracht, Hans-Jürgen; Kluge, Holger; Eder, Klaus; Dräger, Birgit (2008)  Great  globe thistle - a potential new oil crop.  Eur. J. Lipid Sci. Technol. 110, 662 – 667

Brock, Andrea; Brandt, Wolfgang; Dräger, Birgit (2008) The functional  divergence of short-chain dehydrogenases involved in tropinone  reduction. Plant Journal 54, 388 - 401

Freydank, Anna-Carolin; Brandt, Wolfgang; Dräger, Birgit (2008)  Protein structure modeling indicates hexahistidine-tag interference with  enzyme activity.  Proteins 71, 173 - 183

Kvasnička, František; Jocković, Nebojša; Dräger, Birgit; Ševčík, Rudolf; Čepl, Jaroslav; Voldřich Michal (2008)  Electrophoretic  determination of calystegines A3 and B2 in potato. Journal of Chromatography A 1181, 137–144

Biastoff, S. and Dräger, B. (2007) Calystegines. The Alkaloids, Chemistry and Biology, Volume 64 (Cordell, G.A., eds). New York: Academic Press, 49–102.

Robins, Richard. J.; Molinié, Roland; Kwiecien, Rita A.; Paneth, Paul; Lebreton, Julien; Bartholomeusz, Trixie Ann; Roscher, Albert;  Dräger, Birgit; Meier, Anna-Carolin; Mesnard, François (2007)  Progress  in understanding the N-demethylation of alkaloids by exploiting isotopic  techniques. Phytochem. Reviews 6, 51–63

Teuber, Michael.; Meier, Anna-Carolin; Azemi Mohammed Emad; Namyojan, Forough; Wodak, Anja; Brandt, Wolfgang.; Dräger, Birgit (2007) Putrescine N-methyltransferases - A structure-function analysis.  Plant Molecular Biology 63, 787–801

Richter, Ute; Sonnewald, Uwe; Dräger, Birgit (2007)  Calystegines in  potatoes with genetically engineered carbohydrate metabolism.  Journal of Experimental Botany 58 1603 - 1615

Dräger, Birgit (2006) Tropinone reductases, enzymes at the branch point of tropane alkaloid metabolism. Phytochemistry 67, 327–337

Brock, Andrea; Herzfeld, Tobias; Paschke, Reinhard; Koch, Marcus; Dräger, Birgit (2006) Brassicaceae contain nortropane alkaloids. Phytochemistry 67,  2050-2057

Kaiser, Heike; Richter, Ute; Keiner, Ronald; Brabant, Anja; Hause, Bettina; Dräger, Birgit (2006) Immunolocalisation of two tropinone  reductases in potato (Solanum tuberosum L.) root, stolon, and tuber sprouts. Planta 225, 127–137

Biastoff, Stefan; Teuber, Michael; Zhou, Zhaohui Sunny; Dräger, Birgit (2006) Colorimetric activity measurement of a recombinant  putrescine N-methyltransferase from Datura stramonium L.  Planta Medica 72, 1136-1141

Stenzel, Olaf; Teuber, Michael; Dräger, Birgit (2006) Putrescine N-methyltransferase in Solanum tuberosum L., a calystegine-forming plant. Planta 223, 200-212

Dräger, B.; Richter, U. (2005) Calystegine und veränderter Kohlenhydratstoffwechsel in Kartoffeln.  BIOforum 28(9), 27-29

Bartholomeusz, Trixie Ann; Bhogal, Remu K; Molinié, Roland; Felpin, François-Xavier; Mathé-Allainmat, Marie; Meier, Anna-Carolin; Dräger, Birgit; Lebreton, Julien; Roscher, Albert; Robins, Richard. J.; Mesnard, François (2005) Nicotine demethylation in Nicotiana cell suspension cultures: N’-formylnornicotine is not involved. Phytochemistry 66, 1890-1897

Galgon, Tino; Wohlrab, Wolfgang; Dräger, Birgit (2005)  Betulinic  acid induces apoptosis in skin cancer cells and differentiation in  normal human keratinocytes.  Experimental Dermatology 14: 1–9

Boettcher, Chotima.; Fellermeier, Marianne; Boettcher, Christian; Dräger, Birgit; Zenk, Meinhart H. (2005) How human neuroblastoma cells  make morphine. Proceedings of the National Academy of Sciences U.S.A. 102, 8495–8500

Brock, Andrea; Bieri, Stefan; Christen, Philippe; Dräger, Birgit (2005)  Calystegines in wild and cultivated Erythroxylum species. Phytochemistry 66, 1231-1240

Richter, Ute; Rothe, Grit; Fabian, Anne-Kathrin; Rahfeld, Bettina; Dräger, Birgit (2005) Overexpression of tropinone reductases alters  alkaloid composition in Atropa belladonna root cultures.  Journal of Experimental Botany, 56, 645-652

Kaiser, H.; Dräger, B. (2005) Calystegine in Kartoffeln - wo werden sie gebildet? BIOforum 28(3), 34-36

Reviews and Book Chapters

Aehle, Elke; Dräger, Birgit (2010)  Tropane alkaloid analysis by chromatographic and electrophoretic techniques: An update.  Journal of Chromatography B  878, 1391-1406

Mielke,  M. C.; Melzer, E.; Serfling, A.; Ahmetovic, U.; Horbach, R.;  Reimann,  S.; Wohlrab, J.; Dräger, B.; Deising, H. B. (2008)  The  molecular basis  of adaptation to fungicides in plant pathogenic  Colletotrichum  species. In: Modern Fungicides and Antifungal Compounds, S. 63-69. DPG-Verlag Editors H.-W. Dehne et al.

Biastoff, Stefan; Dräger, Birgit (2007) Calystegines. In: The Alkaloids Vol. 64 (Cordell, G. A. ed.) pp. 49 – 102, New York, Academic Press.

Dräger, B. (2006)  Biotechnology of Solanaceae Alkaloids: A Model or an Industrial Perspective?   In: Kayser, O. and Quax, W., Medicinal Plant Biotechnology, Vol. 1, Wiley-VCH Weinheim, Germany, pp 237–265.

Dräger, B.; Richter, U. (2005) Calystegine und veränderter Kohlenhydratstoffwechsel in Kartoffeln. BIOforum 28(9), 27-29

Kaiser, H.; Dräger, B. (2005) Calystegine in Kartoffeln - wo werden sie gebildet? BIOforum 28(3), 34-36

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